Dr. Brent Craven

Education

PhD, Mechanical Engineering, Penn State University (2008)

MS, Mechanical Engineering, Penn State University (2005)

BS, Mechanical Engineering, Penn State Erie, The Behrend College (2003)

Teaching

ME 4327 - Numerical Methods for Engineers

ME 6V97 - Engineering Research

Bio

Dr. Brent Craven is a Professor of Mechanical Engineering at Baylor University. His research focuses on developing and applying computational modeling and simulation (CM&S) to advance medical device innovation and digital health technologies that improve patient outcomes. His research interests include:

· Respiratory fluid dynamics and transport phenomena

· Cardiovascular hemodynamics and fluid-structure interaction (FSI), mechanical blood damage, and the transport of blood clots in the circulatory system

· Cardiovascular devices, including mechanical circulatory support devices (e.g., blood pumps, ventricular assist devices), artificial heart valves and repair devices, and embolic protection or treatment devices (e.g., inferior vena cava blood clot filters, mechanical thrombectomy devices)

· Advancing verification, validation, and uncertainty quantification (VVUQ) methods for medical device CM&S

· Application of in silico clinical trials (ISCTs) to refine, reduce, or replace human subjects in real trials

· Use of CM&S for clinical decision-making (e.g., diagnosis or treatment planning)

Dr. Craven has authored over 60 refereed journal articles and more than 100 conference proceedings and abstracts. He is currently an Associate Editor for the Journal of Verification, Validation and Uncertainty Quantification and Frontiers in Physiology. He is also an active member of the American Society of Mechanical Engineers (ASME) VVUQ 40 subcommittee and a primary contributing author of the ASME VVUQ 40 standard “Assessing Credibility of Computational Modeling through Verification and Validation: Application to Medical Devices.”

Before joining Baylor, Dr. Craven was a Research Scientist and the Senior Science Advisor of Computer Modeling and Simulation in the Center for Devices and Radiological Health (CDRH) at the U.S. Food and Drug Administration (FDA). His research and policy efforts at the FDA primarily focused on advancing computational modeling and VVUQ methods for medical devices. Additionally, he regularly served as a subject matter expert on medical device regulatory submissions. He was a co-lead author of the FDA guidance “Assessing the Credibility of Computational Modeling and Simulation in Medical Device Submissions.” Dr. Craven has received a number of awards for his research and regulatory contributions, including the 2022 FDA Scientific Achievement Award for Excellence in Data and Computational Science, the 2018 FDA CDRH Excellence in Scientific Research Award, and an FDA Commissioner’s Special Citation Award in 2021 for his regulatory contributions in the review of emergency use ventilators.

GOOGLE SCHOLAR PROFILE